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Leadgene offers you a new platform, FOPPR™ INB-D200, for epitope binning service.

It can quickly identify whether antibody clones occupy the same or different epitopes.

The possibility of antibody pairing or co-treatment can also be evaluated by this service.

FOPPR™ Technology

The unique & patented FOPPR™ Technology is combining optical waveguides with noble metal nanoparticles for the sensitive and reliable detection of molecules. In FOPPR™, gold nanoparticles (AuNPs) are in close proximity to an unclad optical fiber. As light propagates within the optical fiber, total internal reflection (TIR) results in an evanescent field that induces the AuNPs to undergo particle plasmon resonance (PPR). When target-analytes interact to AuNPs - conjugated ligands, it will lead to a change of refractive index near the sensing surface.

The extreme sensitivity of this optical property to changes in the surrounding environment makes FOPPR™ an ideal technology for monitoring real-time interactions between a wide range of molecular species, including but not limited to organic drugs, oligonucleotides, proteins, and viruses.



What we can do

  • The new platform - FOPPR™ INB-D200
  • Execute 2 to 4 antibody clones epitope binning with a short of analysis time
  • Time and cost-saving compared to the traditional antibody-paring method
  • Full and detail discussion






Service workflow:

  • Pre-discussion and quotation
  • Case confirmation
  • Case opening
  • Sample providing
  • Affinity analysis
  • Final report delivery
  • Result discussion
  • Case completion


  • For detailed sample requirements, please contact us directly.
    • Purity ≥ 80%
    • Concentration ≥ 0.64 mg/mL
    • Volume ≥ 100 µL
  • Deliverables:
    • A final report (with sample information, affinity results of each pair of samples, including ka, kd and KD, and a epitope binning result of one injection order of antibodies).


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