Leadgene offers a wide range of components for the manufacture of in-vitro diagnostic (IVD) products. These ingredients, known as IVD raw materials, are used in the creation of medical diagnostic tests, devices, and reagents for disease diagnosis. Some of the materials in the collection include antibodies, enzymes, and buffers used in diagnostic test kits. With a focus on providing the best resources for diagnostic development, Leadgene is your go-to source for IVD raw materials.
Package：96 T (8 x 12 strips)
Description：Chronic kidney disease (CKD) often results from hypertension or diabetes. When the kidneys are damaged, the filtration function is blocked, then the wastes and the uremic toxins accumulate in the circulation. Among all uremic toxins, protein-bound toxins such as indoxyl sulfate (IS) are critical to CKD patients. When the glomerular filtration rate decreases, protein-bound toxins become challenging to be cleared in the blood and further damage the renal function and cardiovascular system. In addition, IS will turn on specific genes encoding ROS, free radicals, etc., and increase oxidative stress. Indoxyl sulfate (IS) is a good marker for CKD diagnosis since it directly reflects the glomerular filtration rate. We have a breakthrough in discovering an antibody against the small molecule. And we have launched the CE marked LEADGENE® Indoxyl Sulfate (IS) ELISA Kit.