Human M-CSF, His Tag, HEK293

Catalog Number

LDG026PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    HEK293

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 19.21 kDa.
    The protein migrates as 20 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    LAG-3, or Lymphocyte-activation gene 3, is a protein receptor expressed on the surface of certain immune cells, notably T cells and natural killer cells. It plays a pivotal role in regulating immune responses by inhibiting the activation and proliferation of T cells. LAG-3 is involved in immune tolerance and suppression, making it a promising target for immunotherapy in various diseases, including cancer and autoimmune disorders. Blocking LAG-3 can enhance anti-tumor immune responses, while agonists can suppress excessive immune activation. Studying LAG-3 function provides insights into immune regulation and therapeutic strategies.

    Synonyms

    CSF-1, Lanimostim, Proteoglycan macrophage colony-stimulating factor (PG-M-CSF)

  • Uniprot ID

    P09603

    Sequence Note

    Glu33-Gln181

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant human M-CSF.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.