Human CD1d, His Tag, CHO

Catalog Number

LDG033PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 32.72 kDa.
    The protein migrates as 40-50 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Mycoplasma

    Not detected

  • Form

    Lyophilized

• Background

  • Background

    CD1d protein is a non-classical major histocompatibility complex (MHC) class I-like molecule primarily expressed on antigen-presenting cells, such as dendritic cells and B cells. It presents lipid antigens, including glycolipids and lipopeptides, to natural killer T (NKT) cells. CD1d-NKT cell interaction activates NKT cells, leading to rapid cytokine production and modulation of immune responses. CD1d plays a crucial role in regulating innate and adaptive immunity, autoimmune diseases, and tumor immunosurveillance. Targeting CD1d-NKT cell axis holds promise for therapeutic interventions in cancer, infectious diseases, and autoimmune disorders.

    Synonyms

    Antigen-presenting glycoprotein CD1d, R3G1

  • Uniprot ID

    P15813

    Sequence Note

    Met1-Ser301

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant human CD1d.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.