Varicella Zoster Virus gE, His Tag, HEK293

Catalog Number

LDG026PVM

Datasheet

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• Specifications

  • Species of Origin

    Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

    Expression System

    HEK293

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 62.2 kDa.
    The protein migrates as 60-75 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Mycoplasma

    Not detected

  • Form

    Lyophilized

• Background

  • Background

    Varicella Zoster Virus (VZV) gE is a glycoprotein encoded by the VZV genome, essential for viral replication and pathogenesis. It is primarily involved in viral assembly, maturation, and egress from infected cells. Additionally, gE facilitates viral spread by promoting cell-to-cell fusion, enabling VZV to evade host immune responses and establish persistent infection. The interaction of gE with other viral proteins, such as gI and gB, plays a crucial role in VZV virulence and pathogenicity. Furthermore, gE has been identified as a target for antiviral therapies and vaccine development against VZV infection, including chickenpox and shingles. Understanding the molecular mechanisms underlying gE function provides valuable insights into VZV pathogenesis and offers opportunities for the development of novel therapeutic strategies to combat VZV-related diseases.

    Synonyms

    Envelope glycoprotein E

  • Uniprot ID

    Q9J3M8

    Sequence Note

    Met1-Ala546

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of VZV gE protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.