Leadgene Leadgene
Mouse TNFR-2, His Tag, CHO
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  • Specifications
    • Species of Origin


      Expression System


    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 26.14 kDa.
      The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      TNFR-2, or Tumor Necrosis Factor Receptor 2, is a transmembrane protein found on the surface of various cell types, including immune cells and endothelial cells. It serves as a receptor for Tumor Necrosis Factor-alpha (TNF-alpha), a cytokine involved in inflammation and immune regulation. TNFR-2 signaling modulates cell survival, proliferation, and immune responses, playing a critical role in tissue homeostasis and host defense. Dysregulation of TNFR-2 has been implicated in autoimmune diseases, inflammatory disorders, and cancer. Understanding the molecular mechanisms underlying TNFR-2 signaling is essential for developing targeted therapies to modulate immune responses and treat associated diseases.


      Tumor necrosis factor receptor 2 (TNF-R2), Tumor necrosis factor receptor type II (TNF-RII; TNFR-II), p75, p80 TNF-alpha receptor, CD120b

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse TNFR-2.

    SDS-PAGE analysis of recombinant mouse TNFR-2.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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