-
Species of Origin
Mouse
Expression System
HEK293
-
Affinity Tag
His Tag (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
-
Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 19.9 kDa.
The protein migrates as 28-53 kDa under reducing condition due to glycosylation (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
-
Specifications
-
Background
-
Background
TIM-3 (Havcr2) is an inhibitory immune checkpoint receptor expressed on T cells, NK cells, dendritic cells, and other immune populations. It plays a central role in regulating T cell exhaustion, immune tolerance, and inflammatory responses. TIM-3 also contributes to tumor immune escape by suppressing effector T-cell function.
Synonyms
TIM3, TIMD3, HAVCR2, T-cell immunoglobulin and mucin-domain-containing protein 3, Hepatitis A virus cellular receptor 2, Immune checkpoint receptor TIM3, FLJ14428, KIM3
-
Uniprot ID
Q8VIM0
-
-
Instruction
-
Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
-
Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
-
-
Image
![SDS-PAGE analysis of recombinant Mouse TIM-3.]()
SDS-PAGE analysis of recombinant Mouse TIM-3.
1/1 -
Review
Help others learn more about this product. Use the link below to share your experience.
-
Publication
There are currently no publications. Use the link below to let us know.
-
Datasheet & Documents
1/1
Disclaimer：For Research Use or Further Manufacturing Only.
