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Species of Origin
Mouse
Expression System
CHO
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Affinity Tag
His Tag (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 13.74 kDa.
The protein migrates as 10-60 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a crucial immune checkpoint protein involved in regulating immune responses. It interacts with ligands such as CD155 to inhibit T cell and NK cell functions, influencing immune tolerance and responses in diseases like cancer and autoimmunity. This protein is essential for studying immune modulation and developing targeted therapies. Explore its potential applications in immunotherapy and immunology research to advance understanding and treatment strategies for immune-related disorders.
Synonyms
T cell immunoreceptor with Ig and ITIM domains
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Uniprot ID
NCBI NP_001139797.1
Sequence Note
Gly26-Thr143
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.