Leadgene Leadgene
Mouse TIGIT, His Tag, CHO
Catalog Number

LDG031PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 13.74 kDa.
      The protein migrates as 10-60 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a crucial immune checkpoint protein involved in regulating immune responses. It interacts with ligands such as CD155 to inhibit T cell and NK cell functions, influencing immune tolerance and responses in diseases like cancer and autoimmunity. This protein is essential for studying immune modulation and developing targeted therapies. Explore its potential applications in immunotherapy and immunology research to advance understanding and treatment strategies for immune-related disorders.

      Synonyms

      T cell immunoreceptor with Ig and ITIM domains

    • Uniprot ID

      NCBI NP_001139797.1

      Sequence Note

      Gly26-Thr143

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse TIGIT protein.

    SDS-PAGE analysis of recombinant mouse TIGIT protein.

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  • Datasheet & Documents
    MSDS
    Manual
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