Mouse IL-6R, His Tag, CHO

Catalog Number

LDG137PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 40.1 kDa.
    The protein migrates as 50-75 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Interleukin-6 receptor subunit alpha (IL-6R, also known as CD126) is a membrane glycoprotein that binds IL-6 and mediates signal transduction through its association with gp130. IL-6R plays a critical role in immune regulation, inflammation, and hematopoiesis, and is implicated in various pathological conditions including autoimmune diseases, cancers, and cardiovascular disorders. The soluble form (sIL-6R) extends IL-6 responsiveness to cells lacking membrane-bound IL-6R.

    Synonyms

    IL6R, Interleukin-6 receptor alpha chain, CD126 antigen, gp80, soluble IL-6 receptor, IL-6RA, cytokine receptor family member 18

  • Uniprot ID

    P22272

    Sequence Note

    Met1-Glu357

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant Mouse IL-6R protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.