Leadgene Leadgene
Mouse IL-18BP, His Tag, CHO
Catalog Number

LDG080PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated 18.8 MW of kDa.
      The protein migrates as 15-45 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind mouse IL-18 in functional ELISA. Immobilized Recombinant mouse IL-18 Protein at 2 μg/mL (100μL/well) can bind Recombinant Mouse IL-18BP Protein.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      IL-18 binding protein (IL-18BP) is a natural inhibitor of IL-18, a cytokine involved in inflammation and immune responses. IL-18BP regulates immune activity and is a target for treating autoimmune diseases.

      Synonyms

      Interleukin-18-binding protein, IL-18BP, Tadekinig-alfa

    • Uniprot ID

      Q9Z0M9

      Sequence Note

      Thr29-Ala193

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse IL-18BP

    SDS-PAGE analysis of recombinant mouse IL-18BP

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  • Datasheet & Documents
    MSDS
    Manual
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