Mouse ICAM, His Tag, CHO

Catalog Number

LDG023PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 51.06 kDa.
    The protein migrates as 65-93 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    ICAM (Intercellular Adhesion Molecule) protein is a cell surface glycoprotein expressed on various cell types, including endothelial cells, leukocytes, and epithelial cells. It plays a key role in mediating cell-cell adhesion and facilitating leukocyte extravasation during inflammatory responses. ICAM interactions with integrin receptors on leukocytes are essential for immune cell recruitment to sites of inflammation and tissue injury. Moreover, ICAM expression is upregulated in response to inflammatory stimuli, contributing to the amplification of immune responses. Understanding ICAM's functions is crucial for elucidating mechanisms of immune regulation and developing targeted therapies for inflammatory diseases.

    Synonyms

    MALA-2, MyD10, CD54

  • Uniprot ID

    NP_034623.1

    Sequence Note

    Met1-Asn485

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant mouse ICAM.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.