Leadgene Leadgene
Mouse ICAM, His Tag, CHO
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  • Specifications
    • Species of Origin


      Expression System


    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 51.06 kDa.
      The protein migrates as 65-93 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      ICAM (Intercellular Adhesion Molecule) protein is a cell surface glycoprotein expressed on various cell types, including endothelial cells, leukocytes, and epithelial cells. It plays a key role in mediating cell-cell adhesion and facilitating leukocyte extravasation during inflammatory responses. ICAM interactions with integrin receptors on leukocytes are essential for immune cell recruitment to sites of inflammation and tissue injury. Moreover, ICAM expression is upregulated in response to inflammatory stimuli, contributing to the amplification of immune responses. Understanding ICAM's functions is crucial for elucidating mechanisms of immune regulation and developing targeted therapies for inflammatory diseases.


      MALA-2, MyD10, CD54

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse ICAM.

    SDS-PAGE analysis of recombinant mouse ICAM.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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