Leadgene Leadgene
Mouse EpCAM, His Tag, CHO
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  • Specifications
    • Species of Origin


      Expression System


    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 28.46 kDa.
      The protein migrates as 30-35 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      EpCAM (Epithelial Cell Adhesion Molecule), a transmembrane glycoprotein, is expressed in epithelial tissues and various carcinomas. It mediates cell-cell adhesion and signaling, influencing cell proliferation, migration, and differentiation. EpCAM is involved in maintaining epithelial integrity and regulating epithelial-mesenchymal transition (EMT) during development and tissue repair. Additionally, it serves as a diagnostic and prognostic marker in cancer, where its overexpression correlates with tumor aggressiveness and poor clinical outcomes. EpCAM-targeted therapies, including monoclonal antibodies and immunotherapies, hold promise in cancer treatment. Understanding EpCAM's roles in physiology and pathology is crucial for developing effective therapeutic strategies.


      Epithelial cell adhesion molecule, Epithelial glycoprotein 314 (EGP314; mEGP314), Protein 289A, Tumor-associated calcium signal transducer 1, CD326

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse EpCAM.

    SDS-PAGE analysis of recombinant mouse EpCAM.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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