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TW
Leadgene Leadgene
Mouse CD83, His Tag, CHO
Catalog Number

LDG012PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 13.11 kDa.
      The protein migrates as 25-40 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CD83, a transmembrane protein primarily found on the surface of mature dendritic cells, is a key regulator of immune responses. It plays a critical role in modulating T cell activation and tolerance. CD83 expression is upregulated upon dendritic cell maturation and is involved in antigen presentation and T cell priming. Additionally, CD83 can also be found in soluble form, exerting immunoregulatory effects on T cells and other immune cells. Its precise functions in immune regulation are still under investigation, but CD83 is recognized as a potential therapeutic target for immune-related disorders and autoimmune diseases.

      Synonyms

      CD83 antigen

    • Uniprot ID

      O88324

      Sequence Note

      Met1-Arg133

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD83.

    SDS-PAGE analysis of recombinant mouse CD83.

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  • Datasheet & Documents
    MSDS
    Manual
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