Leadgene Leadgene
Mouse CD79 Bata, His Tag, HEK293
Catalog Number

LDG123PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression System

      HEK293

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 15.65 kDa.
      The protein migrates as 23-35 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CD79B, also known as the Igβ chain, is a critical signaling component of the B-cell antigen receptor (BCR) complex. Together with CD79A (Igα), CD79B mediates antigen recognition and transduces activation signals required for B cell development, differentiation, and immune responses. Phosphorylation of CD79B initiates downstream signaling cascades, including SYK, BTK, and NF-κB pathways. Recombinant CD79B expressed in HEK293 cells is commonly used for antibody screening, BCR signaling studies, and immunological assay development.

      Synonyms

      Igβ, B29, MB-1 beta chain homolog, CD79 beta chain, CD79B antigen, Immunoglobulin-associated beta chain, B-cell receptor-associated protein β, Ig-beta protein, B-cell antigen receptor Igβ subunit, CD79B_MOUSE, BCR membrane signaling subunit, IgM receptor β chain, IgD receptor β chain, B lymphocyte antigen receptor beta chain, BCR complex component β, B-cell signaling adapter, β subunit of BCR complex, B-cell activation molecule, BCR scaffold protein, Immune receptor signal transduction protein, B-cell lineage surface protein, CD79b

    • Uniprot ID

      P15530

      Sequence Note

      Val26-Asp158

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Mouse CD79B.

    SDS-PAGE analysis of recombinant Mouse CD79B.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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