Leadgene Leadgene
Mouse CD40, His Tag, CHO
Catalog Number

LDG033PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 18.96 kDa.
      The protein migrates as 12-27 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CD40 is a cell surface receptor belonging to the tumor necrosis factor (TNF) receptor superfamily, expressed primarily on antigen-presenting cells such as B cells, dendritic cells, and macrophages. It plays a pivotal role in immune responses by mediating interactions between these cells and T cells, crucial for antibody production, inflammation, and immune regulation. Our product targets CD40 to modulate these signaling pathways, potentially influencing immune activation and response. Through extensive research, we have developed a solution designed to interact selectively with CD40, offering a specialized approach for therapeutic interventions in conditions where immune dysregulation is a concern.

      Synonyms

      Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor

    • Uniprot ID

      P27512

      Sequence Note

      Met1-Arg193

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD40 protein.

    SDS-PAGE analysis of recombinant mouse CD40 protein.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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