Leadgene Leadgene
Mouse CD38, His Tag, CHO
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  • Specifications
    • Species of Origin


      Expression System


    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 30.61 kDa.
      The protein migrates as 36-42 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      CD38, a transmembrane glycoprotein, is widely expressed on immune cells such as B cells, T cells, and natural killer cells, as well as non-immune cells like endothelial cells. It functions as a multifunctional enzyme with ADP-ribosyl cyclase activity, catalyzing the conversion of NAD+ to cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate. CD38 regulates calcium signaling, cell adhesion, and differentiation, playing essential roles in immune responses and inflammation. Moreover, CD38 is also a therapeutic target in multiple myeloma, where its expression correlates with disease progression. Understanding CD38's diverse functions is crucial for developing targeted therapies in immunology and oncology.


      2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1 (ADPRC 1), Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1), I-19, NIM-R5 antigen

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD38.

    SDS-PAGE analysis of recombinant mouse CD38.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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