Leadgene Leadgene
Mouse CD16, His Tag, CHO
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  • Specifications
    • Species of Origin


      Expression System


    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 21.87 kDa.
      The protein migrates as 30-45 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      CD16, also known as Fc gamma receptor III (FcγRIII), is a transmembrane protein primarily found on the surface of natural killer (NK) cells, macrophages, and a subset of T cells. It plays a critical role in mediating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis. CD16 binds to the Fc portion of immunoglobulin G (IgG) antibodies, facilitating the recognition and destruction of target cells or pathogens coated with antibodies. This interaction activates downstream signaling pathways, triggering cytotoxic responses. CD16's involvement in immune surveillance and host defense highlights its significance in immune regulation and therapeutic strategies targeting ADCC.


      Fc gamma receptor III

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD16.

    SDS-PAGE analysis of recombinant mouse CD16.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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