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Species of Origin
Mouse
Expression System
CHO
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Affinity Tag
His Tag (N-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 26.69 kDa.
The protein migrates as 35-45 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
ASGPR (Asialoglycoprotein Receptor) protein is primarily expressed on hepatocytes, facilitating the clearance of circulating glycoproteins lacking terminal galactose residues. It plays a crucial role in regulating liver homeostasis and clearance of desialylated glycoproteins from circulation. ASGPR's specificity for desialylated glycoproteins makes it a valuable target for drug delivery and liver-specific therapies. Moreover, ASGPR expression levels vary among individuals and can be altered in liver diseases, making it a potential diagnostic marker. Understanding ASGPR's functions in liver physiology and pathology is essential for developing targeted therapies and diagnostic tools for liver-related disorders.
Synonyms
Asialoglycoprotein receptor 1, ASGP-R 1, ASGPR 1, Hepatic lectin 1 (HL-1; mHL-1)
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Uniprot ID
NP_033844.1
Sequence Note
Ser60-Asn284
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.