Leadgene Leadgene
Mouse ASGPR, His Tag, CHO
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  • Specifications
    • Species of Origin


      Expression System


    • Affinity Tag

      His Tag (N-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 26.69 kDa.
      The protein migrates as 35-45 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      ASGPR (Asialoglycoprotein Receptor) protein is primarily expressed on hepatocytes, facilitating the clearance of circulating glycoproteins lacking terminal galactose residues. It plays a crucial role in regulating liver homeostasis and clearance of desialylated glycoproteins from circulation. ASGPR's specificity for desialylated glycoproteins makes it a valuable target for drug delivery and liver-specific therapies. Moreover, ASGPR expression levels vary among individuals and can be altered in liver diseases, making it a potential diagnostic marker. Understanding ASGPR's functions in liver physiology and pathology is essential for developing targeted therapies and diagnostic tools for liver-related disorders.


      Asialoglycoprotein receptor 1, ASGP-R 1, ASGPR 1, Hepatic lectin 1 (HL-1; mHL-1)

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse ASGPR.

    SDS-PAGE analysis of recombinant mouse ASGPR.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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