Human TSP1, His Tag, CHO

Catalog Number

LDG196PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >85% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 128.7 kDa.
    The protein migrates as 160-170 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Thrombospondin-1 (TSP1), encoded by THBS1, is a multifunctional extracellular matrix glycoprotein involved in cell–cell and cell–matrix interactions. It regulates angiogenesis, cell adhesion, migration, apoptosis, and tissue remodeling. TSP1 is a major endogenous activator of latent TGF-β and plays important roles in fibrosis, wound healing, inflammation, and tumor progression. Dysregulated TSP1 expression has been associated with cardiovascular disease, chronic kidney disease, and cancer, making it an important target in cell biology and disease-related research.

    Synonyms

    Thrombospondin-1, TSP, TSP-1, THBS1, THBS-1, THBS, Platelet glycoprotein G, Glycoprotein thrombospondin, Anti-angiogenic matricellular protein

  • Uniprot ID

    P07996

    Sequence Note

    Asn19-Pro1170

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant Human TSP1 Protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.