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Species of Origin
Human
Expression System
HEK293
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Affinity Tag
Fc Tag (N-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 39.1 kDa.
The protein migrates as 40-43 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
Transforming growth factor beta 3 (TGF-β3), encoded by TGFB3, is a multifunctional cytokine belonging to the TGF-β superfamily. It regulates cell proliferation, differentiation, extracellular matrix production, and immune responses through SMAD-dependent and SMAD-independent signaling pathways. TGF-β3 plays important roles in embryonic development, tissue repair, fibrosis modulation, and tumor progression. Dysregulation of TGF-β3 signaling has been associated with fibrotic diseases, chronic inflammatory conditions, and cancer, making it a key factor in cell biology and disease-related research.
Synonyms
Transforming growth factor beta 3, TGFβ3, TGFB3, TGFβ-3, TGFB-3, TGF beta 3, Growth differentiation factor 3-related cytokine, Fibrosis-associated cytokine
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Uniprot ID
P10600
Sequence Note
Ala301-Ser412
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.