Leadgene Leadgene
Human TGF Beta 3, Fc Tag, HEK293
Catalog Number

LDG194PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      HEK293

    • Affinity Tag

      Fc Tag (N-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 39.1 kDa.
      The protein migrates as 40-43 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Transforming growth factor beta 3 (TGF-β3), encoded by TGFB3, is a multifunctional cytokine belonging to the TGF-β superfamily. It regulates cell proliferation, differentiation, extracellular matrix production, and immune responses through SMAD-dependent and SMAD-independent signaling pathways. TGF-β3 plays important roles in embryonic development, tissue repair, fibrosis modulation, and tumor progression. Dysregulation of TGF-β3 signaling has been associated with fibrotic diseases, chronic inflammatory conditions, and cancer, making it a key factor in cell biology and disease-related research.

      Synonyms

      Transforming growth factor beta 3, TGFβ3, TGFB3, TGFβ-3, TGFB-3, TGF beta 3, Growth differentiation factor 3-related cytokine, Fibrosis-associated cytokine

    • Uniprot ID

      P10600

      Sequence Note

      Ala301-Ser412

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human TGF Beta 3 Protein.

    SDS-PAGE analysis of recombinant Human TGF Beta 3 Protein.

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  • Datasheet & Documents
    MSDS
    Manual
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