Leadgene Leadgene
Human SCF, His Tag, CHO
Catalog Number

LDG191PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >85% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 19.3 kDa.
      The protein migrates as 20-35 kDa under reducing condition due to glycosylation (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Stem cell factor (SCF), also known as KIT ligand (KITLG) or steel factor, is a hematopoietic cytokine that binds to the c-Kit receptor (CD117) to regulate cell survival, proliferation, differentiation, and migration. SCF plays essential roles in hematopoiesis, mast cell development, melanocyte function, and germ cell maintenance. Dysregulated SCF–c-Kit signaling has been implicated in cancer progression and tumor microenvironment regulation. SCF is widely used in cell biology, immunology, cancer research, and organoid culture systems to support stem and progenitor cell growth and signaling studies.

      Synonyms

      Stem cell factor, SCF, KIT ligand, KITLG, Steel factor, Mast cell growth factor, c-Kit ligand, Hematopoietic growth factor

    • Uniprot ID

      P21583

      Sequence Note

      Glu26-Ala189

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human SCF protein.

    SDS-PAGE analysis of recombinant Human SCF protein.

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  • Datasheet & Documents
    MSDS
    Manual
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