Leadgene Leadgene
Human RANKL, His Tag, CHO
Catalog Number

LDG117PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His Tag (N-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 21.28 kDa.
      The protein migrates as 25-55 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Receptor activator of nuclear factor κB ligand (RANKL) regulates osteoclast differentiation and bone resorption. It is essential for bone metabolism and immune response.

      Synonyms

      Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Cleaved into: Tumor necrosis factor ligand superfamily member 11, membrane form, soluble form

    • Uniprot ID

      O14788

      Sequence Note

      Gly64-Asp245

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      "This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles."

  • Image
    SDS-PAGE analysis of recombinant Human RANKL.

    SDS-PAGE analysis of recombinant Human RANKL.

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  • Datasheet & Documents
    MSDS
    Manual
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