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Species of Origin
Human
Expression System
CHO
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Affinity Tag
His Tag (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 13.65 kDa.
The protein migrates as 20-25 kDa under reducing condition (SDS-PAGE analysis). -
Activity
Measured by flow cytometry for its ability to bind a ligand expressed in K562 human chronic myelogenous leukemia cells.
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
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Form
Lyophilized
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Specifications
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Background
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Background
Natural cytotoxicity triggering receptor 3 (NKp30), also known as CD337, is an activating receptor expressed on natural killer (NK) cells. It plays a crucial role in NK cell-mediated cytotoxicity against tumor and virus-infected cells by recognizing ligands such as B7-H6 and heparan sulfate glycosaminoglycans. NKp30 is also involved in the cross-talk between NK cells and dendritic cells, influencing immune responses.
Synonyms
Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NKp30, CD337
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Uniprot ID
O14931
Sequence Note
Leu19-Gly135
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Image
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Review
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.