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Catalog Number

LDG061PHM

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Specifications
- Species of Origin
  
  Human
  
  Expression System
  
  HEK293
- Affinity Tag
  
  His Tag (C-term)
  
  Storage Buffer
  
  Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
- Purity
  
  >95% as determined by SDS-PAGE analysis.
  
  Molecular weight
  
  The protein has a calculated MW of 24.38 kDa.
  The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).
- Activity
  
  Measured by its ability to bind human beta-NGF in functional ELISA. Immobilized Recombinant human beta-NGF at 5 μg/mL (100 μL/well) can bind Recombinant Human NGFR Protein.
  
  Endotoxin Level
  
  <0.1 EU per 1 μg of the protein by the LAL method.
- Form
  
  Lyophilized
Background
- Background
  
  Human nerve Growth Factor Receptor (NGFR), also known as p75NTR, is a receptor for neurotrophins, including nerve growth factor. It is involved in the regulation of neuronal survival, growth, and apoptosis, playing a key role in the nervous system development and injury response.
  
  Synonyms
  
  Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR, p75 ICD, CD271
- Uniprot ID
  
  P08138
  
  Sequence Note
  
  Lys29-Asn 250
Instruction
- Reconstitution
  
  It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
  
  Shipping
  
  The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
- Stability & Storage
  
  This product is stable after storage at:
  - -20°C for 12 months in lyophilized state from date of receipt.
  - -20°C or -80°C for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
Image

Activity analysis of recombinant Human NGFR, His Tag, HEK293.
Measured by its ability to bind human beta-NGF in functional ELISA. Immobilized Recombinant human beta-NGF at 5 μg/mL (100 μL/well) can bind Recombinant Human NGFR Protein.

HPLC analysis of recombinant Human NGFR, His Tag, HEK293.
The purity of Human NGFR Protein is greater than 95% as determined by RP-HPLC.

SDS-PAGE analysis of recombinant Human NGFR.

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Datasheet & Documents

Datasheet

MSDS

Manual

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