Leadgene Leadgene
Human MMP-2, His-Avi Tag, HEK293
Catalog Number

LDG185PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      HEK293

    • Affinity Tag

      His-Avi Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >85% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 73.5 kDa.
      The protein migrates as 68-72 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Matrix metalloproteinase-2 (MMP2), also known as Gelatinase A or 72 kDa type IV collagenase, is a zinc-dependent endopeptidase involved in the degradation of extracellular matrix (ECM) components, particularly type IV collagen. MMP2 is secreted as a proenzyme and activated extracellularly, playing a pivotal role in tissue remodeling, angiogenesis, wound healing, and embryonic development. Dysregulated MMP2 expression is associated with cancer progression, metastasis, cardiovascular diseases, and inflammatory disorders.

      Synonyms

      MMP-2, Gelatinase A, 72 kDa type IV collagenase, Clg4a, TBE-1, EC 3.4.24.24, Matrix metallopeptidase 2, MMP2, GelA

    • Uniprot ID

      P08253

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human MMP-2.

    SDS-PAGE analysis of recombinant Human MMP-2.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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