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Leadgene Leadgene
Human Latent Activin A, His Tag, CHO
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Catalog Number

LDG170PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 45.9 kDa.
      The protein migrates as 40-45 kDa and 10-15 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <50 ng/mL.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Mycoplasma

      Not detected

      Form

      Lyophilized

  • Background
    • Background

      Human Activin A is a member of the TGF-β superfamily involved in cell growth, differentiation, and immune regulation. It plays key roles in reproductive biology and is also linked to inflammation, fibrosis, and cancer. As a recombinant protein, Activin A is widely used in stem cell research and disease modeling.

      Synonyms

      Activin beta-A, INHBA, Activin A

    • Uniprot ID

      P08476

      Sequence Note

      Ser21-Ser426

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    Activity analysis of recombinant Human Latent Activin A, His tag, CHO. Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is &lt;50 ng/mL. 

    Activity analysis of recombinant Human Latent Activin A, His tag, CHO.
    Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <50 ng/mL. 

    SDS-PAGE analysis of recombinant human latent Activin A.

    SDS-PAGE analysis of recombinant human latent Activin A.

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  • Datasheet & Documents
    MSDS
    Manual
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