Leadgene Leadgene
Human IL-4R Alpha, His Tag, HEK293
Catalog Number

LDG067PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      HEK293

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 24.56 kDa.
      The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human IL-4 in functional ELISA. Immobilized Recombinant human IL-4 at 1 μg/mL (100 μL/well) can bind Recombinant Human IL-4R Alpha Protein.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Interleukin-4 Receptor Alpha (IL-4Rα) is a receptor subunit that binds IL-4 and IL-13, mediating immune responses, particularly in allergic inflammation and asthma. It is crucial in the regulation of Th2 cell differentiation.

      Synonyms

      Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124, Soluble interleukin-4 receptor subunit alpha, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding protein, IL4-BP

    • Uniprot ID

      P24394

      Sequence Note

      Met26 - His232

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human IL-4R Alpha.

    SDS-PAGE analysis of recombinant Human IL-4R Alpha.

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  • Datasheet & Documents
    MSDS
    Manual
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