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Leadgene Leadgene
Human HGF, His Tag, HEK293
Catalog Number

LDG021PHM

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  • Overview

    Description

    Hepatocyte Growth Factor (HGF) activates c-Met receptor's tyrosine kinase cascade, influencing cell growth and motility. Originating from mesenchymal cells, HGF is a multifunctional cytokine that plays a central role in angiogenesis, tumorigenesis, and tissue regeneration. Initially secreted as an inactive polypeptide, HGF undergoes cleavage to become an active heterodimeric molecule. The gene exhibits alternative splicing, resulting in diverse isoforms.

  • Specifications
    • Species of Origin

      Human

      Expression System

      HEK293 cell

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 80.48 kDa.
      The protein migrates as 75-100 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Uniprot ID

      P14210

      Sequence Note

      Gln 32-Ser 728

  • Instruction
    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

      Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human HGF.

    SDS-PAGE analysis of recombinant human HGF.

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  • Datasheet & Documents
    MSDS
    Manual
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