Description
Hepatocyte Growth Factor (HGF) activates c-Met receptor's tyrosine kinase cascade, influencing cell growth and motility. Originating from mesenchymal cells, HGF is a multifunctional cytokine that plays a central role in angiogenesis, tumorigenesis, and tissue regeneration. Initially secreted as an inactive polypeptide, HGF undergoes cleavage to become an active heterodimeric molecule. The gene exhibits alternative splicing, resulting in diverse isoforms.
Species of Origin
Human
Expression System
HEK293
Affinity Tag
His Tag (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
Purity
>90% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 80.48 kDa.
The protein migrates as 75-100 kDa under reducing condition (SDS-PAGE analysis).
Endotoxin Level
<1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
Uniprot ID
P14210
Sequence Note
Gln 32-Ser 728
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
Stability & Storage
This product is stable after storage at:
Avoid repeated freeze/thaw cycles.
SDS-PAGE analysis of recombinant human HGF.
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Disclaimer：For Research Use or Further Manufacturing Only.
