Leadgene Leadgene
Human Her2, His-SUMO Tag, HEK293
Catalog Number

LDG177PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      HEK293

    • Affinity Tag

      His-SUMO Tag (N-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >85% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 80.89 kDa.
      The protein migrates as 90-100 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human Her2 Antibody in functional ELISA. Immobilized Recombinant human Her2 Protein can bind human Her2 Antibody.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Human Her2 (Human Epidermal Growth Factor Receptor 2, also known as ERBB2 or CD340) is a receptor tyrosine kinase involved in cell growth and differentiation. Overexpression of Her2 is associated with various cancers, particularly breast cancer, and it serves as a key biomarker and therapeutic target in oncology research and diagnostics.

      Synonyms

      ERBB2, CD340, HER-2, NEU, HER2, MLN19, NGL, TKR1, p185HER2

    • Uniprot ID

      P04626

      Sequence Note

      Thr23-Thr652

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human Her2 protein.

    SDS-PAGE analysis of recombinant Human Her2 protein.

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  • Datasheet & Documents
    MSDS
    Manual
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