Leadgene Leadgene
Human FCGR1, His Tag, CHO
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Catalog Number

LDG153PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 31.8 kDa.
      The protein migrates as 35-100 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human IgG in functional ELISA. Immobilized Recombinant human IgG at 1 μg/mL (100 μL/well) can bind Recombinant Human FCGR1 Protein.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Fc gamma receptor I (FCGR1) is a high-affinity receptor for the Fc region of IgG antibodies. It is expressed on the surface of various immune cells, including macrophages and monocytes, and is involved in processes such as phagocytosis and antibody-dependent cellular cytotoxicity.

      Synonyms

      High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, CD64

    • Uniprot ID

      P12314

      Sequence Note

      Gln16-His292

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    Activity analysis of recombinant Human FCGR1, His Tag, CHO. Measured by its ability to bind human IgG in functional ELISA. Immobilized Recombinant human IgG at 1 μg/mL (100 μL/well) can bind Recombinant Human FCGR1 Protein.

    Activity analysis of recombinant Human FCGR1, His Tag, CHO.
    Measured by its ability to bind human IgG in functional ELISA. Immobilized Recombinant human IgG at 1 μg/mL (100 μL/well) can bind Recombinant Human FCGR1 Protein.

    SDS-PAGE analysis of recombinant human FCGR1.

    SDS-PAGE analysis of recombinant human FCGR1.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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