Leadgene Leadgene
Human FAP, His Tag, CHO
Catalog Number

LDG089PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His Tag (N-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 85.85 kDa.
      The protein migrates as 70-100 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human FAP Antibody in functional ELISA. Immobilized Recombinant human FAP Protein can bind human FAP Antibody.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Fibroblast activation protein (FAP) is a serine protease expressed in cancer-associated fibroblasts and plays a role in tumor growth and metastasis.

      Synonyms

      Prolyl endopeptidase FAP, EC:3.4.21.26, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, EC:3.4.14.5, Fibroblast activation protein alpha, FAP alpha, Gelatine degradation protease FAP, EC:3.4.21.-, Integral membrane serine protease, Post-proline cleaving enzyme, Serine integral membrane protease, SIMP, Surface-expressed protease, Seprase, APCE

    • Uniprot ID

      Q12884

      Sequence Note

      Leu26-Asp761

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human FAP.

    SDS-PAGE analysis of recombinant Human FAP.

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  • Datasheet & Documents
    MSDS
    Manual
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