Leadgene Leadgene
Human EGFR, His Tag, CHO
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Catalog Number

LDG036PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 69.42 kDa.
      The protein migrates as 72-130 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human EGF in functional ELISA. Immobilized Recombinant human EGF Protein at 2 μg/mL (100μL/well) can bind Recombinant Human EGFR Protein.

      Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      EGFR (Epidermal Growth Factor Receptor) is a transmembrane protein involved in signaling pathways that regulate cell growth, proliferation, and survival. It plays a crucial role in various cellular processes and is implicated in cancer development and progression. Our product targets EGFR to potentially inhibit these pathways, offering a therapeutic approach for cancer treatment. Through rigorous research, we have developed a solution designed to interact selectively with EGFR, aiming to modulate its activity and disrupt cancer cell growth. This product represents a significant advancement in precision medicine for EGFR-driven cancers.

      Synonyms

      Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

    • Uniprot ID

      P00533

      Sequence Note

      Met1-Ser645

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    HPLC analysis of recombinant Human EGFR, His Tag, CHO. The purity of Human EGFR Protein is greater than 95% as determined by SEC-HPLC.

    HPLC analysis of recombinant Human EGFR, His Tag, CHO.
    The purity of Human EGFR Protein is greater than 95% as determined by SEC-HPLC.

    SDS-PAGE analysis of recombinant human EGFR protein.

    SDS-PAGE analysis of recombinant human EGFR protein.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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