Human EGFR, His Tag, CHO

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Catalog Number

LDG036PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 69.42 kDa.
    The protein migrates as 72-130 kDa under reducing condition (SDS-PAGE analysis).

  • Activity

    Measured by its ability to bind human EGF in functional ELISA. Immobilized Recombinant human EGF Protein at 2 μg/mL (100μL/well) can bind Recombinant Human EGFR Protein.

    Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Form

    Lyophilized

• Background

  • Background

    EGFR (Epidermal Growth Factor Receptor) is a transmembrane protein involved in signaling pathways that regulate cell growth, proliferation, and survival. It plays a crucial role in various cellular processes and is implicated in cancer development and progression. Our product targets EGFR to potentially inhibit these pathways, offering a therapeutic approach for cancer treatment. Through rigorous research, we have developed a solution designed to interact selectively with EGFR, aiming to modulate its activity and disrupt cancer cell growth. This product represents a significant advancement in precision medicine for EGFR-driven cancers.

    Synonyms

    Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

  • Uniprot ID

    P00533

    Sequence Note

    Met1-Ser645

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  HPLC analysis of recombinant Human EGFR, His Tag, CHO.
  The purity of Human EGFR Protein is greater than 95% as determined by SEC-HPLC.

  SDS-PAGE analysis of recombinant human EGFR protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.