Human Complement C1s, His Tag, HEK293

Catalog Number

LDG163PHM

Datasheet

More Documents

Loading package & price...

COA Search

• Specifications

  • Species of Origin

    Human

    Expression System

    HEK293

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated 75.71 MW of kDa.
    The protein migrates as 74-75 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Complement C1s is a calcium-dependent serine protease and a key component of the C1 complex in the classical complement pathway. Upon activation, C1s cleaves C4 and C2, leading to the formation of C3 convertase and downstream complement activation. C1s plays a crucial role in innate immunity, immune complex clearance, and antibody-mediated defense. Recombinant C1s expressed in HEK293 cells is widely applied in complement research, immunology, and diagnostic reagent development.

    Synonyms

    Complement C1s subcomponent, EC:3.4.21.42, C1 esterase, Complement component 1 subcomponent s, Cleaved into: Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain

  • Uniprot ID

    P09871

    Sequence Note

    Glu16-Asp688

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant Human Complement C1s.

  1

  /

  1

  Total   (1)

• Review

  

  Help others learn more about this product. Use the link below to share your experience.

  Submit a Review

• Publication

  

  There are currently no publications. Use the link below to let us know.

  Submit a Publication

• Datasheet & Documents

  Datasheet

  MSDS

  Manual

  1

  /

  1

Disclaimer：For Research Use or Further Manufacturing Only.