Leadgene Leadgene
Human CD38, His-Avi Tag, CHO
Catalog Number

LDG161PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      Avi+His (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 32.5 kDa.
      The protein migrates as 36-46 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CD38 is a multifunctional enzyme expressed on the surface of many immune cells, including plasma cells. It functions in the metabolism of cyclic ADP-ribose, influencing calcium signaling. CD38 is also a marker for cell activation and differentiation. In clinical settings, CD38 is a target for therapeutic antibodies in diseases like multiple myeloma.

      Synonyms

      ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, EC:3.2.2.-, EC:3.2.2.6, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, EC:2.4.99.20, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPR hydrolase 1, T10, CD38

    • Uniprot ID

      P28907

      Sequence Note

      Val43-Ile300

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human CD38.

    SDS-PAGE analysis of recombinant human CD38.

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  • Datasheet & Documents
    MSDS
    Manual
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