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Species of Origin
Human
Expression System
CHO
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Affinity Tag
Avi+His (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 32.5 kDa.
The protein migrates as 36-46 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
CD38 is a multifunctional enzyme expressed on the surface of many immune cells, including plasma cells. It functions in the metabolism of cyclic ADP-ribose, influencing calcium signaling. CD38 is also a marker for cell activation and differentiation. In clinical settings, CD38 is a target for therapeutic antibodies in diseases like multiple myeloma.
Synonyms
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, EC:3.2.2.-, EC:3.2.2.6, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, EC:2.4.99.20, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPR hydrolase 1, T10, CD38
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Uniprot ID
P28907
Sequence Note
Val43-Ile300
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.