Leadgene Leadgene
Human CD19, Fc Tag, CHO
Catalog Number

LDG186PHM

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  • Specifications
    • Species of Origin

      Human

      Expression System

      CHO

    • Affinity Tag

      His-Avi Tag(N-term)
      Human IgG1 Fc Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 58.72 kDa.
      The protein migrates as 62-75 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Human CD19 is a B-lymphocyte-specific cell surface glycoprotein and a key regulator of B-cell receptor signaling. It plays a critical role in B-cell development, activation, and immune response modulation. CD19 is widely used as a biomarker for B-cell malignancies and autoimmune diseases, and serves as a therapeutic target for monoclonal antibody and CAR-T cell therapies.

      Synonyms

      B-lymphocyte antigen CD19, CVID3, Leu-12, T-cell surface antigen Leu-12, B-cell surface antigen CD19, CD19, B4, MGC12802

    • Uniprot ID

      P15391

      Sequence Note

      Glu21-Lys291

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human CD19.

    SDS-PAGE analysis of recombinant Human CD19.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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