Human BLyS, His Tag, CHO

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Catalog Number

LDG046PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 17.87 kDa.
    The protein migrates as 16-18 kDa under reducing condition (SDS-PAGE analysis).

  • Activity

    Measured by its ability to bind human BAFF in functional ELISA. Immobilized Recombinant human BAFF Protein at 1 μg/mL (100 μL/well) can bind Recombinant Human BLyS Protein.

    Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Form

    Lyophilized

• Background

  • Background

    BLyS (B Lymphocyte Stimulator), also known as BAFF (B-cell Activating Factor), is a cytokine crucial for B-cell survival and maturation. It plays a key role in regulating B-cell homeostasis and antibody production. Our product targets BLyS to modulate B-cell activity, potentially influencing immune responses in conditions like autoimmune diseases and B-cell malignancies. Through advanced scientific research, we have developed a solution aimed at selectively interacting with BLyS, offering a promising approach to therapeutic intervention in disorders where B-cell dysregulation is a concern.

    Synonyms

    Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator (BLyS), B-cell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1 (TALL-1), CD257

  • Uniprot ID

    GenBank: AAH20674.1

    Sequence Note

    Ala134-Leu285

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  HPLC analysis of recombinant Human BLyS, His Tag, CHO.
  The purity of Human BLyS Protein is greater than 95% as determined by RP-HPLC.

  SDS-PAGE analysis of recombinant Human BLyS.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.