Leadgene Leadgene
Human ACE2, Fc Tag, HEK293
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  • Specifications
    • Species of Origin


      Expression System

      HEK293 cell

    • Affinity Tag

      Mouse IgG2b Fc Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >98% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 109.67 kDa.
      The protein migrates as 120-170 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.



  • Background
    • Background

      Angiotensin-Converting Enzyme 2 (ACE2) has a function as an enzyme that hydrolysis the angiotensin II into angiotensin which do the effect of anti-oxidation and anti-inflammatory in cardiovascular system through the inhibition of MAPK pathway and TGF β signaling pathway. ACE2 is highly expression in intestines, kidney, and heart. It is also fonud highy expression in patients with lung cancer.


      Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, ACEH, Angiotensin-converting enzyme-related carboxypeptidase, ACE-related carboxypeptidase, Metalloprotease MPROT15

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human ACE2.

    SDS-PAGE analysis of recombinant human ACE2.

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  • Publication
  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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