Description
The p24 protein of HIV-1 plays a critical role as a core structural component essential for virus assembly. Its measurement serves as an indicator of HIV-1 infection. AIDS symptoms and a decline in CD4 T-cell count usually manifest approximately two weeks following HIV infection, showing a correlation with elevated levels of both the virus and p24 protein. Additionally, a reduction in p24 antibody levels proves to be a valuable prognostic marker.
Species of Origin
Human Immunodeficiency Virus
Expression System
Escherichia coli
Affinity Tag
His Tag (N-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
Purity
>90% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 26.52 kDa.
The protein migrates as 22-24 kDa under reducing condition (SDS-PAGE analysis).
Endotoxin Level
<1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
Synonyms
Gag
Uniprot ID
P04591
Sequence Note
Pro133 - Leu363
Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
Stability & Storage
This product is stable after storage at:
Avoid repeated freeze/thaw cycles.
SDS-PAGE analysis of HIV-1 capsid protein p24.
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Disclaimer：For Research Use or Further Manufacturing Only.
