C. difficile Toxin B Protein, His tag, E. coli

Catalog Number

LDG024POE

Datasheet

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• Specifications

  • Species of Origin

    Clostridium difficile

    Expression System

    Escherichia coli

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 63.93 kDa.
    The protein migrates as 60 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Clostridium difficile enterotoxin B is a protein produced by the bacterium Clostridium difficile. It plays a crucial role in the pathogenesis of C. difficile-associated diseases, particularly in causing damage to the intestinal mucosa and inducing inflammation. This toxin disrupts cellular integrity by targeting specific receptors on the host cell surface, leading to cell death and tissue damage. Understanding the mechanisms of action of this toxin is essential for developing effective treatments and vaccines against C. difficile infections.

    Synonyms

    Glucosyltransferase TcdB, toxB

  • Uniprot ID

    P18177

    Sequence Note

    Met1-Leu543

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant toxin B.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.