Metallothioneins (MTs) is a group of low-molecular-weight, cysteine-rich, non-enzymatic proteins, is involved in storage, transportation and binding of metals, and plays a critical role in the protection against metal toxicity and oxidative stress. Metallothionein-3 (MT-3；also known as Growth Inhibitory Factor, GIF), a member of the MTs family, is mainly expressed in the central nervous system, can protect neuronal cells from oxidative stress via its anti-oxidant properties. MT-3 is abnormally under-expressed in the brains of Alzheimer's disease patients.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.