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Leadgene Leadgene
Mouse Napsin A, His Tag, CHO
Catalog Number

LDG006PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 44.64 kDa.
      The protein migrates as 40-70 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Napsin A is a biomarker protein primarily found in the human lung and kidney tissues. It belongs to the aspartic proteinase family and plays a crucial role in the maturation of pulmonary surfactant proteins, aiding in respiratory function. Elevated levels of Napsin A have been linked to certain lung diseases, including adenocarcinoma, making it a valuable diagnostic marker in pathology. Its specificity to lung tissue makes it a promising target for immunohistochemical staining in the diagnosis and classification of lung cancer subtypes. Napsin A's significance in both normal physiology and disease pathology underscores its importance in medical research and clinical practice.

      Synonyms

      KDAP-1, Kidney-derived aspartic protease-like protein (KAP)

    • Uniprot ID

      O09043

      Sequence Note

      Met1-Gly419

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse Napsin A.

    SDS-PAGE analysis of recombinant mouse Napsin A.

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  • Datasheet & Documents
    MSDS
    Manual
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