The CXC chemokine is a group of secreted proteins, attracts neutrophils and lymphocytes. Interleukin-8 (IL-8, or CXCL8), a member of the CXC chemokines, is a proinflammatory cytokine produced by macrophages and other cell types like endothelial cells, epithelial cells and airways smooth muscle cells. This cytokine mainly attracts and activates neutrophils to the site of inflammation and also plays an important role in cell proliferation, tissue remodeling and angiogenesis.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.