The CXC chemokine is a group of secreted proteins, attracts neutrophils and lymphocytes. CXC chemokine ligand 12 (CXCL12 or Stromal cell-derived factor 1, SDF-1), a member of the CXC chemokines, exists in three alternative splicing variants (α, β and γ). This chemokine plays a crucial role in embryogenesis, hematopoiesis, angiogenesis and inflammation. CXCL12 is the only chemokine ligand for CXCR4, this ligand-receptor pair is essential during embryogenesis, hematopoiesis, and immune system organization.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.