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Leadgene Leadgene
Anti-β-amyloid Antibody [Clone 85-1]
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Catalog Number

LDG0103YA

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  • Overview

    Description

    Beta-amyloid (Aβ) is one of the intrinsically disordered proteins (IDPs) involved in Alzheimer's disease (AD) pathogenesis. This peptide derives from the sequential cleavage of a transmembrane glycoprotein, amyloid precursor protein (APP), by beta secretase and gamma secretase. The abnormal metabolism of APP result in excessive accumulation of Aβ, and triggers neurofibrillary tangles, oxidative stress, microglial activation, synaptic dysfunction, synaptic loss and the inflammatory response.

    Product Note

    Recommended dilution factor:
    ELISA: 1:5000-20000
    WB:1: 1000-5000



    Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.

  • Specifications
    • Host

      Mouse

      Clonality

      Monoclonal

    • Isotype

      IgG2a

      Clone Name

      clone 85-1

    • Immunogen

      Human beta-amyloid 1-42

      Reactivity

      Human

    • Application

      ELISA, WB

      Conjugation

      Unconjugated

    • Concentration

      1 mg/mL

      Buffer

      Phosphate Buffered Saline containing 0.01% thimerosal, pH 7.4.

    • Specificity

      Beta Amyloid (1-42)

      Form

      Liquid

  • Instruction
    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

      Stability & Storage

      This product is stable after storage at:

      • 2-8°C for 2 weeks under sterile conditions from date of receipt.
      • -20°C or -80°C for 12 months under sterile conditions from date of receipt.

      Avoid repeated freeze/thaw cycles.
      Suggestion: Divide antibody into several vials. Keep only vials for usage at 2-8°C.

  • Image
    ELISA titration of Anti-β-amyloid (1-42) Antibody [clone 85-1]

    ELISA titration of Anti-β-amyloid (1-42) Antibody [clone 85-1]

    Dot blot analysis of Anti-β-amyloid (1-42) Antibody [clone 85-1].

    Dot blot analysis of Anti-β-amyloid (1-42) Antibody [clone 85-1].

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  • Datasheet & Documents
    MSDS
    Manual
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