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Leadgene Leadgene
SARS-CoV-2 Trimeric Spike Protein, His Tag, HEK293
Catalog Number

LDG010PHM

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  • Specifications
    • Species of Origin

      SARS-CoV-2

      Expression system

      HEK293 cell

    • Affinity Tag

      His Tag (C-term)

      Concentration

      Please refer to the product label.

    • Buffer

      Liquid. Phosphate buffered saline, pH 7.4.

      Purity

      >95% as determined by SDS-PAGE analysis.

    • Molecular weight

      The protein has a calculated MW of 137.94 kDa.
      The protein migrates above 180 kDa under reducing condition (SDS-PAGE analysis).

      Form

      Liquid

  • Background
    • Background

      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a 2019 novel coronavirus, that causes pandemic disease globally. SARS-CoV-2 is a single-stranded RNA virus that belongs to the Coronaviridae family. Structurally, the virus harbors sixteen non-structural proteins (NSP1-NSP16), four structural proteins (spike, membrane, envelope, and nucleocapsid), and nine accessory proteins. The spike protein is a 1273-amino-acids transmembrane, homotrimeric class I fusion protein that contains two functional subunits, receptor-binding subunit S1 (amino acids 14-685) and membrane-fusion subunit S2 (amino acids 686-1273). The trimeric spike protein on the surface of the virion is responsible for initiating viral infection through binding to the angiotensin-converting enzyme 2 (ACE2) receptor on host cells.

      Synonyms

      Spike glycoprotein, E2, Peplomer protein, S glycoprotein

    • Uniprot ID

      #P0DTC2

      Sequence Note

      Ser13-Pro1213

  • Instruction
    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -80°C or lower for long term storage.

      Stability & Storage

      This product is stable after storage at:

      • -80°C for long-term storage under sterile conditions.

      Avoid repeated free-thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant SARS-CoV-2 trimeric spike protein.

    SDS-PAGE analysis of recombinant SARS-CoV-2 trimeric spike protein.

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  • Publication
  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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