Product Note
This recombinant protein is also available in a His-Avi tag format, suitable for subsequent biotinylation applications. Please feel free to contact us if needed.
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Overview
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Specifications
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Species of Origin
Mouse
Expression system
CHO
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Affinity Tag
His Tag (N-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 80.41 kDa.
The protein migrates as 93-130 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Background
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Background
PSMA (Prostate-Specific Membrane Antigen) protein, a transmembrane glycoprotein, is highly expressed in prostate epithelial cells and overexpressed in prostate cancer. It serves as a marker for prostate cancer diagnosis, staging, and prognosis. PSMA's enzymatic activity allows it to cleave specific substrates, facilitating nutrient uptake and tumor growth. PSMA-targeted imaging and therapy, utilizing radiolabeled ligands, show promise in detecting and treating prostate cancer. Furthermore, PSMA-based therapies are being explored for other PSMA-expressing cancers. Understanding PSMA's role in prostate cancer biology is crucial for developing targeted diagnostics and therapeutics to improve patient outcomes.
Synonyms
Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase (FGCP), Glutamate carboxypeptidase II (GCPII), Membrane glutamate carboxypeptidase (mGCP), N-acetylated-alpha-linked acidic, dipeptidase I (NAALADase I), Prostate-specific membrane antigen homolog, Pteroylpoly-gamma-glutamate carboxypeptidase
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Uniprot ID
O35409
Sequence Note
Ile44-Ala752
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Image
![SDS-PAGE analysis of recombinant mouse PSMA.]()
SDS-PAGE analysis of recombinant mouse PSMA.
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Review
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Publication
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Datasheet & Documents
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Disclaimer：For Research Use or Further Manufacturing Only.
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