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Species of Origin
Mouse
Expression system
CHO
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>90% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 13.27 kDa.
The protein migrates as 32-36 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
Podoplanin (PDPN) is a type I transmembrane glycoprotein expressed in lymphatic endothelial cells, fibroblasts, alveolar type I cells, and various tumor cells. PDPN promotes lymphangiogenesis, regulates cell adhesion and migration, and interacts with CLEC-2 on platelets to drive metastasis and thrombosis. It serves as a key marker for lymphatic vessels, cancer-associated fibroblasts (CAFs), and tumor microenvironment remodeling, making recombinant PDPN valuable for cancer, immunology, and vascular biology research.
Synonyms
Podoplanin, Glycoprotein 38, Gp38, OTS-8, PA2.26 antigen, Transmembrane glycoprotein E11, E11, Ots8
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Uniprot ID
Q62011
Sequence Note
Gly23-Leu141
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.