Leadgene Leadgene
Mouse PDPN, His Tag, CHO
Catalog Number

LDG110PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 13.27 kDa.
      The protein migrates as 32-36 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Podoplanin (PDPN) is a type I transmembrane glycoprotein expressed in lymphatic endothelial cells, fibroblasts, alveolar type I cells, and various tumor cells. PDPN promotes lymphangiogenesis, regulates cell adhesion and migration, and interacts with CLEC-2 on platelets to drive metastasis and thrombosis. It serves as a key marker for lymphatic vessels, cancer-associated fibroblasts (CAFs), and tumor microenvironment remodeling, making recombinant PDPN valuable for cancer, immunology, and vascular biology research.

      Synonyms

      Podoplanin, Glycoprotein 38, Gp38, OTS-8, PA2.26 antigen, Transmembrane glycoprotein E11, E11, Ots8

    • Uniprot ID

      Q62011

      Sequence Note

      Gly23-Leu141

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Mouse PDPN.

    SDS-PAGE analysis of recombinant Mouse PDPN.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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