Leadgene Leadgene
Mouse LAG3, His Tag, HEK293
Catalog Number

LDG041PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      HEK293

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 49.28 kDa.
      The protein migrates as 50-55 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Mouse lymphocyte-Activation Gene 3 (LAG3) is an immune checkpoint receptor expressed on activated T cells and regulatory T cells. It negatively regulates T cell proliferation and function, playing a crucial role in maintaining immune homeostasis and preventing autoimmunity.

      Synonyms

      Lymphocyte activation gene 3 protein, LAG-3, Activation-induced cytidine deaminase-linked autoimmunity protein, Aida, CD223, Secreted lymphocyte activation gene 3 protein, sLAG-3

    • Uniprot ID

      Q61790

      Sequence Note

      Gly24 - Leu442

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Mouse LAG3.

    SDS-PAGE analysis of recombinant Mouse LAG3.

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  • Datasheet & Documents
    MSDS
    Manual
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