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Species of Origin
Mouse
Expression system
Escherichia coli
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>98% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 18.2 kDa.
The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis). -
Activity
Measure by its ability to induce proliferation in CTLL-2 cells. The ED₅₀ for this effect is <15 ng/mL.
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
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Form
Lyophilized
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Specifications
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Background
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Background
Interleukin-2 (IL-2) is a 18 kDa four bundle, immuno-modulatory cytokine which is expressed predominately by antigen-simulated CD4+ T cells, CD8+ T cells, natural killer (NK) cells, and dendritic cells (DC). IL-2 plays a fundamental role in promoting NK cell proliferation, cytotoxicity, and B cells differentiation. IL-2 modulate T cell differentiation programs, promoting naïve CD4+ T cell differentiation into T helper-1 (Th1) and T helper-2 (Th2) cells.
Synonyms
Interleukin-2, T-cell Growth Factors , TCGF
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Uniprot ID
P04351
Sequence Note
Ala21-Gln169
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Image
![Activity analysis of recombinant Mouse IL-2, His Tag, E. coli. Measure by its ability to induce proliferation in CTLL-2 cells. The ED₅₀ for this effect is <15 ng/mL.]()
Activity analysis of recombinant Mouse IL-2, His Tag, E. coli.
Measure by its ability to induce proliferation in CTLL-2 cells. The ED₅₀ for this effect is <15 ng/mL.![SDS-PAGE analysis of recombinant mouse IL-2.]()
SDS-PAGE analysis of recombinant mouse IL-2.
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Publication
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Datasheet & Documents
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Disclaimer：For Research Use or Further Manufacturing Only.
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