Mouse FOLR1, His Tag, CHO

Catalog Number

LDG026PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression system

    CHO

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 25.08 kDa.
    The protein migrates as 30-40 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    FOLR1 (Folate Receptor Alpha) protein is a cell surface receptor that binds to and internalizes folate (vitamin B9). It plays a crucial role in folate metabolism and cellular uptake of folate, essential for DNA synthesis, repair, and methylation. FOLR1 is highly expressed in various cancers, including ovarian, lung, and breast cancer, making it a potential therapeutic target for cancer treatment. Additionally, FOLR1-targeted imaging and drug delivery systems show promise in cancer diagnosis and therapy. Understanding FOLR1's functions in folate homeostasis and cancer biology is essential for developing targeted therapies and diagnostic tools for folate-related disorders and cancers.

    Synonyms

    Folate receptor alpha, FR-alpha, Folate receptor 1, Folate-binding protein 1

  • Uniprot ID

    P35846

    Sequence Note

    Met1-Ser232

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant mouse FOLR1.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.